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FRENCH INFRASTRUCTURE FOR INTEGRATED STRUCTURAL BIOLOGY

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INSTRUCT CENTRE - FRANCE 2 - ISBG

ELECTRON MICROSCOPY

The EM platform provides three types of services

  1. verify the homogeneity of a sample (aggregated or not).
  2. determine the degree of oligomerization of a protein.
  3. allow image analysis and 3D reconstruction of protein complexes (collaboration).

The cryo-electron microscopes, and the associated instruments, are available under conditions.

Different techniques are available in the platform to allow the observation of biological samples

1. Fixation

2. Inclusion

3. Sectioning

4. Labeling and Staining

5. Observation

The platform also provides access to equipments under certain conditions
Scientific collaborations, that require specific developments, are possible .

See more at:

http://www.isbg.fr/structural-analysis/cryo-electron-microscopy/

https://www.structuralbiology.eu/update/platform/cryo-em-on-polara-in-grenoble-france/