The SAXS platform at the CBS relies on experimental measurements performed on bioSAXS synthrotron beamlines (SWING at SOLEIL, BM29 at ESRF, and P12 at Petra-III). The platform has a strong expertise in data analysis using original methods developed during the last two decades.
The platform mainly focuses on the structural and dynamic characterization of flexible biomolecules such as intrinsically disordered and multi-domain proteins. SAXS data are integrated into computational tools and combined with structural information derived from other techniques (X-ray crystallography, NMR, and EM) or bioinformatics.