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FRENCH INFRASTRUCTURE FOR INTEGRATED STRUCTURAL BIOLOGY

TRAINING

FRISBI offers a range of workshops to train graduate and post-graduate students in integrated structural biology. FRISBI courses are open to french and european researchers, from academic and industry.


 Cryo-EM Sample Preparation Practical Course (Grenoble, May 2026)

The eighth hands-on “Instruct — FRISBI — PSB Grenoble Cryo-EM Course on Sample Preparation”, jointly organised by the ESRF, EMBL Grenoble, and the IBS, continuing a series initiated in 2018.

📍 Location: European Photon and Neutron Campus, Grenoble, France  

📆 Dates: May 19–22, 2026  

📝 Application deadline: April 12, 2026  

The course will cover both theoretical and practical aspects of sample preparation, including iterative grid screening and evaluation for sample optimization. Participants will have access to state-of-the-art instrumentation (2× Glacios, 2× Titan Krios, 4× Vitrobot), as well as a demonstration of cryo-FIB milling (2× Aquilos), providing insight into how single-particle cryo-EM connects to cryo-ET workflows.

There is no registration fee. Meals and accommodation will be provided free of charge; however, participants are responsible for their travel to and from Grenoble.

A maximum of 16 participants will be selected. Participants may bring their own samples for testing, subject to suitability.

Applications are now open. Successful applicants will be notified within one week of the deadline.

Please complete the survey following the link below in order to be considered: 

https://workshops.ibs.fr/survey/index.php/614337?lang=en 

This 3-day workshop is aimed at PhD students, postdoctoral researchers, staff scientists, and team leaders who are new to the field of single-particle cryo-EM.

Contact: cryo-em@ibs.fr 

This in-person workshop is co-funded by INSTRUCT and FRISBI (ISBG), with additional support from Thermo Fisher Scientific.


ReNaFoBis / FRISBI webinar

Please find below the program of the next FRISBI/ReNaFoBis webinar on Production –April 2nd at 01:00 PM Paris

Speaker: Béatrice Vibert from Univ. Grenoble Alpes, CNRS, CEA, Institut de Biologie Structurale (IBS),Title: Cell-free Synthesis of Isotopically Labelled Antibody Fragments for Structural Characterization by NMR 

Speaker: Finn McGhee from the Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Title: “Cell-free expression of recombinant viral membrane assembly proteins for characterization by cryo-electron tomography

Please register here https://grist.numerique.gouv.fr/o/docs/forms/5FQqgcjx4zQrAD81C69wLC/55

Deadline for registration April 1th at 03:00 PM Paris

We will send you the webinar link few days before the webinar.


BioStine

FRISBI support BioStine a site to access the basics in Structural Biology in French Biostine FR , or in English Biostine EN

Une play-list youtube dédiée à la Biologie Structurale Intégrative (Coordination: Marie-Hélène Le Du, Paris-Saclay): https://www.youtube.com/playlist?list=PLJXFANNaperht_5i-UzBTvCLAH0-CbIg6

Biostine on the PDB newsletter , January 2026


Past webinars:

March, 19, 2026 Speaker: Raffaele IEVA, CBI, Toulouse, FranceTitle: HDX-MS characterizes lateral gate dynamics of enterobacterial outer membrane proteins. Speaker: Hugo GIZARDIN-FREDON, Joannes Gutenberg Universität Mainz, Germany.Title: “Advanced cross-linking mass spectrometry workflows for integrative structural biology”

February 12, 2026 Sigrid Milles, Berlin, Germany Title: Intrinsically disordered regulators of endocytosis – an integrated NMR/single molecule fluorescence approach”

January 15th 2026  Aurélie Bertin Institut Curie Title:  Cryo-tomography : a useful tool to study membrane remodeling proteins using reconstituted systems. Denis Chrétien Université de Rennes Title : C- and D-lattices: The missing link between microtubule structure and dynamic instability? 

November 20, 2025: Speaker: Charles Kervrann, Inria Rennes, Institut Curie, France Title: Deep learning and Convolutional Neural Network for Macromolecule detection and Identification in 3D Cryo-Cellular Tomograms. Speaker 2 : Hugues Nury, IBS Grenoble, France Tittle: RDL receptor and the application of AI-guided protein design for developing safer insecticides.

October 16, 2025: Speaker : Philippe Carpentier: Laboratoire de Chimie et Biologie des Métaux, DRF/IRIG/CBM, UMR 5249 CEA/CNRS/UGA, CEA/Grenoble, Title: Pressurizing crystals at the HPMX laboratory to unlock the internal architecture, dynamics, and mechanisms of proteins. Speaker: Mael Balanec: I2BC Paris Saclay Title: Structural understanding of site-specific recombination by XerC/XerD in Vibrio cholerae"

September 18, 2025: Speaker: Darren Hart, IBS/ISBG Grenoble Title: The French Infrastructure for Integrated Structural Biology (FRISBI) - current status and future plans.

July 10, 2025: Paris Leandro Estrozi, IBS, Grenoble Title: Helical Symmetry Determination for 3D Cryo-Electron Microscopy and Denis Chrétien, Université de Renes Title: C- and D-type lateral interactions weaken the microtubule lattice

May 15, 2025  Marc Jamin, IBS, Grenoble, France Title: Deciphering the mechanisms of liquid phase separation induced by rabies virus phosphoprotein

April 24, 2025Speaker: Simon Pichard, IGBMC/CBI, Illkirch, France Tittle: Eukaryotic production and characterization of multi-protein complexes: tools and examples and Speaker: Amélie Zachayus, IGBMC, France Title: New Models, New Insights: How CRISPR-Cas9 and Live-Cell Analysis can be used to Enhance Our Understanding of Cellular Mechanisms: the example of the transcription/DNA repair factor TFIIH

March 13, 2025 Speaker: Claude Sauter, IBMC, Strasbourg, France Tittle: Microfluidic chips for biomolecular crystal growth and serial crystallography; Serena Sirigu, SOLEIL, Paris-Saclay, France Tittle: In-situ X-ray crystallography with the CRIBLEUR on the PROXIMA-2A beamline at Synchrotron SOLEIL

February 13, 2025 Speaker: Tobias Madl University of Graz, Austria Tittle "Decoding the Regulatory Role of Post-Translational Modifications with NMR Spectroscopy"

January 23, 2025 Speaker: Nils Marechal, IGBMC/CBI, Illkirch, France Title: Streptavidin affinity grids for structural electron microscopy

December 12, 2024 2 speakers: Marta Janczuk-Richter, Creoptix AG, Wädenswil, Switzerland Title: Pushing the boundaries in biomolecular interaction analysis with the Creoptix WAVEsystem and Eric Ennifar, IBMC, Strasbourg, France Title: A multi-approach benchmarking of macromolecular interactions - Focus on kinITC
November 14, 2024 2 speakers: Lionel Imbert, IBS, Grenoble, France Title: Overview of cell-free protein production & developments for NMR samples and Martin Pelosse, EMBL Grenoble Title: Eukaryotic expression strategies at the EEF.
October 17, 2024 Speaker: François Ferron, AFMB Tittle: Structural Approach to characterize the Metabolic Activation Pathway Of a Nucleotide analogue: From Pro-Drug to Target
September 12, 2024  2 speakers: Alicja Razew (IBS, Grenoble) Tittle: Antibiotic Resistance: How to Monitor Drug-Protein Interactions in the Bacterial Periplasm and Christina Sizun (ICSN, Gif sur Yvette) Tittle: A dual binding mode between RSV NS1 and MED25 contributes to reshaping of antiviral responses.
June 25, 2024 Florian FAESSLER (IGBMC, Illkirch) Title: Cryo-electron tomography of filament assemblies and their organizers
May 14, 2024 Speaker: Agathe Urvoas, Institute for Integrative Biology of the Cell (I2BC), Tittle: AlphaRep: a new platform dedicated to the selection of artificial protein binders

Please follow our program of ReNaFoBis-FRISBI webinars


FRISBI is involved and strongly support the French National training network in structural biology (ReNaFoBiS).  Aimed to be a national PhD training network, ReNaFoBiS coordinate and organize classes, workshops and training programs for students and post-docs.


13ieme Ecole de Biologie Structurale Integrative du 5au 12 juin 2026 à Oleron 13ieme Ecole de Biologie Structurale Intégrative - Sciencesconf.org

Date limite de dépot de candidature : 01 mars 2026.


See http://www.renafobis.fr/   for more information