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FRENCH INFRASTRUCTURE FOR INTEGRATED STRUCTURAL BIOLOGY

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CBS

SMALL ANGLE X-RAY SCATTERING

The SAXS platform at the CBS is managed by Dr Pau Bernadó (http://www.cbs.cnrs.fr/index.php/en/home-equipea2). It relies on experimental measurements performed on bioSAXS synthrotron beamlines (BM29 at ESRF, SWING at SOLEIL, and P12 at Petra-III). The platform has a strong expertise in data analysis developed during the last decade. The platform mainly focuses on the structural and dynamic characterization of flexible biomolecules such as intrinsically disordered and multi-domain proteins. SAXS data are integrated into computational tools and combined with structural information derived from other techniques (X-ray, crystallography, NMR, and EM) or bioinformatics.