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FRENCH INFRASTRUCTURE FOR INTEGRATED STRUCTURAL BIOLOGY

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CENTERS

INSTRUCT CENTER - FRANCE 1 - IGBMC

The IGBMC created in 1994 is one of the main European research centres in biomedical research, involving the Inserm, CNRS and the University of Strasbourg. In addition to its four scientific programs, the IGBMC has developed advanced scientific services and technological platforms for internal use, but also open to the wider scientific community. The Institute aims to develop interdisciplinary research at the interface of biology, biochemistry, physics and medicine, but also to attract students from around the world by offering very high-level education in the field of biomedical sciences.

Structural biology has a long tradition in Strasbourg and started from small molecule and protein crystallography to gradually integrate bioinformatics, molecular modelling, NMR and electron microscopy. It has become a centre of expertise unique in France for the structure determination of proteins and their complexes with DNA and RNA, mainly related to human health, notably those involved inthe regulation of gene expression (transcription, translation) with the specificity of integration of high sensitivity state-of-the-art equipment (crystallography, electron-microscopy and NMR) to target the multi-scale 3D structure-function analysis of biological processes at all resolution levels and dynamic ranges from the molecule to the cell.

Platforms

The IGBMC-CERBM offers access for: